iShares U.S. Pharmaceuticals ETF

iShares U.S. Pharmaceuticals ETF

About

iShares U.S. Pharmaceuticals ETF (US4642888360) is a US-listed equity ETF tracking the Dow Jones U.S. Select Pharmaceuticals Index. With a expense ratio of 0.38%, it is moderately priced, paying distributions. The fund holds 60 positions across 1 region with 956M in assets, with heavy concentration — 100% in United States, 100% in Health Care.

Score Breakdown

Scores are scaled 1–10 on a logarithmic curve relative to all ETFs in the database. Last updated: Jun 22, 2026
Component Score Details
Cost (30%) 7.9 Tracking Difference: 10.0 · TD Consistency: — · Expense Ratio: 3.0
Liquidity (25%) 8.1 Assets Under Management

Data sources: provider factsheets, exchange data, and NAV history. Information for educational purposes only — not investment advice.

Ticker IHE
ISIN
Fund Size $956.4M
Issuer iShares
Distribution Pays Distributions
Replication Physical
Inception May 2006
Base Currency USD
Index Dow Jones U.S. Select Pharmaceuticals Index
Asset Class Equities
Category Equity Sector

Costs

7.9
This fund has low total costs, with competitive tracking and expense ratios.

Cost Metrics Explained

What expense ratio, tracking difference, and TD consistency measure

Expense ratio (Total Expense Ratio) is the annual fee the fund charges, deducted from assets. It’s the headline cost, but not the full picture.

Tracking Difference measures how much the fund actually lags (or leads) its benchmark index per year. This is the single best measure of true cost — it captures the expense ratio plus all other drags like sampling error and tax withholding. A lower (or negative) value is better.

TD Consistency measures how stable the tracking difference is from year to year. A low value means predictable, reliable costs; a high value means costs can vary significantly.

Expense Ratio0.00%
 
Metric Value
Expense Ratio 0.38%

Cumulative Returns

Performance across different time periods.
Year to Date+0.00%
1 Year+0.00%
3 Years+0.00%
5 Years+0.00%
Inception+0.00%
 
Period Cumulative Return
1 Month
3 Months
6 Months
1 Year +43.63%
3 Years +19.02%
5 Years +10.26%
10 Years +8.15%
YTD +8.58%
Since Inception +10.49%

Holdings

This fund invests into 60 individual investments.
#1
Eli Lilly & Co
22.00%
#2
Johnson & Johnson
21.79%
#3
Pfizer Inc
4.48%
#4
Royalty Pharma PLC
4.42%
#5
Bristol-Myers Squibb Co
4.42%
#6
Viatris Inc
4.41%
#7
Zoetis Inc
4.41%
#8
Merck & Co Inc
4.35%
#9
Jazz Pharmaceuticals PLC
3.47%
#10
Elanco Animal Health Inc
2.98%
View all holdings (50)
# Holding Ticker Weight
1 Eli Lilly & Co LLY 2199.76%
2 Johnson & Johnson JNJ 2179.09%
3 Pfizer Inc PFE 448.16%
4 Royalty Pharma PLC RPRX 442.07%
5 Bristol-Myers Squibb Co BMY 441.99%
6 Viatris Inc VTRS 441.09%
7 Zoetis Inc ZTS 440.65%
8 Merck & Co Inc MRK 435.14%
9 Jazz Pharmaceuticals PLC JAZZ 347.37%
10 Elanco Animal Health Inc ELAN 298.10%
11 Axsome Therapeutics Inc AXSM 266.84%
12 Corcept Therapeutics Inc CORT 188.15%
13 Ligand Pharmaceuticals Inc LGND 135.76%
14 Liquidia Corp LQDA 123.04%
15 Indivior Pharmaceuticals Inc INDV 115.07%
16 Crinetics Pharmaceuticals Inc CRNX 93.20%
17 Organon & Co OGN 86.91%
18 Amneal Pharmaceuticals Inc AMRX 68.82%
19 Edgewise Therapeutics Inc EWTX 68.32%
20 Definium Therapeutics Inc DFTX 65.80%
21 Supernus Pharmaceuticals Inc SUPN 63.48%
22 Tarsus Pharmaceuticals Inc TARS 61.61%
23 Prestige Consumer Healthcare Inc PBH 54.83%
24 Nektar Therapeutics NKTR 50.77%
25 Enliven Therapeutics Inc ELVN 50.77%
26 Trevi Therapeutics Inc TRVI 49.98%
27 Alumis Inc ALMS 49.13%
28 Ocular Therapeutix Inc OCUL 40.71%
29 Innoviva Inc INVA 38.86%
30 ANI Pharmaceuticals Inc ANIP 35.72%
31 VERADERMICS INC MANE 35.16%
32 Harrow Inc HROW 35.05%
33 Perrigo Co PLC PRGO 34.95%
34 Nuvation Bio Inc NUVB 33.40%
35 Harmony Biosciences Holdings Inc HRMY 32.76%
36 Amylyx Pharmaceuticals Inc AMLX 32.63%
37 Xeris Biopharma Holdings Inc XERS 29.57%
38 MBX Biosciences Inc MBX 28.26%
39 Collegium Pharmaceutical Inc COLL 26.81%
40 Rapport Therapeutics Inc RAPP 26.41%
41 EyePoint Inc EYPT 26.37%
42 WaVe Life Sciences Ltd WVE 23.07%
43 Pacira BioSciences Inc PCRX 21.65%
44 Septerna Inc SEPN 20.49%
45 AtaiBeckley Inc ATAI 19.52%
46 OMEROS CORP OMER 18.34%
47 LB Pharmaceuticals Inc LBRX 18.02%
48 MAZE THERAPEUTICS INC MAZE 17.86%
49 Phibro Animal Health Corp PAHC 16.54%
50 BIOAGE LABS INC BIOA 16.38%

Sectors

Allocation by industry sector.
 
Sector Weight
Health Care 9951.00%
Unknown 49.00%

Regions

Geographic allocation by country of risk.
 
Country Weight
United States 9951.00%
UNKNOWN 49.00%
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