iShares Genomics Immunology and Healthcare ETF

iShares Genomics Immunology and Healthcare ETF

About

iShares Genomics Immunology and Healthcare ETF (US46435U1925) is a US-listed equity ETF tracking the NYSE FactSet Global Genomics and Immuno Biopharma Index (USD) (Net). With a expense ratio of 0.47%, its costs are on the higher end for an ETF, paying distributions. The fund holds 69 positions across 9 regions with 168M in assets, with heavy concentration — 59% in United States, 93% in Health Care.

Score Breakdown

Scores are scaled 1–10 on a logarithmic curve relative to all ETFs in the database. Last updated: Jun 22, 2026
Component Score Details
Cost (30%) 7.7 Tracking Difference: 10.0 · TD Consistency: — · Expense Ratio: 2.2
Liquidity (25%) 6.2 Assets Under Management

Data sources: provider factsheets, exchange data, and NAV history. Information for educational purposes only — not investment advice.

Ticker IDNA
ISIN
Fund Size $167.7M
Issuer iShares
Distribution Pays Distributions
Replication Physical
Inception Jun 2019
Base Currency USD
Index NYSE FactSet Global Genomics and Immuno Biopharma Index (USD) (Net)
Asset Class Equities
Category Thematic Equity

Costs

7.7
This fund has low total costs, with competitive tracking and expense ratios.

Cost Metrics Explained

What expense ratio, tracking difference, and TD consistency measure

Expense ratio (Total Expense Ratio) is the annual fee the fund charges, deducted from assets. It’s the headline cost, but not the full picture.

Tracking Difference measures how much the fund actually lags (or leads) its benchmark index per year. This is the single best measure of true cost — it captures the expense ratio plus all other drags like sampling error and tax withholding. A lower (or negative) value is better.

TD Consistency measures how stable the tracking difference is from year to year. A low value means predictable, reliable costs; a high value means costs can vary significantly.

Expense Ratio0.00%
 
Metric Value
Expense Ratio 0.47%

Cumulative Returns

Performance across different time periods.
Year to Date+0.00%
1 Year+0.00%
3 Years+0.00%
5 Years+0.00%
Inception+0.00%
 
Period Cumulative Return
1 Month
3 Months
6 Months
1 Year +49.95%
3 Years +8.95%
5 Years -7.76%
10 Years
YTD +14.33%
Since Inception +3.77%

Holdings

This fund invests into 69 individual investments.
#1
Moderna Inc
5.15%
#2
Twist Bioscience Corp
4.83%
#3
REVOLUTION Medicines Inc
4.17%
#4
Bayer AG
3.97%
#5
Biontech Se
3.94%
#6
Genmab A/S
3.89%
#7
Vertex Pharmaceuticals Inc
3.86%
#8
Takeda Pharmaceutical Co Ltd
3.80%
#9
Exelixis Inc
3.76%
#10
Ipsen SA
3.76%
View all holdings (50)
# Holding Ticker Weight
1 Moderna Inc MRNA 514.95%
2 Twist Bioscience Corp TWST 483.15%
3 REVOLUTION Medicines Inc RVMD 417.17%
4 Bayer AG BAYN 396.60%
5 Biontech Se BNTX 394.13%
6 Genmab A/S GMAB 389.22%
7 Vertex Pharmaceuticals Inc VRTX 386.06%
8 Takeda Pharmaceutical Co Ltd 4502 380.50%
9 Exelixis Inc EXEL 376.22%
10 Ipsen SA IPN 375.87%
11 GSK PLC GSK 375.06%
12 Roche Holding AG ROP 367.13%
13 Regeneron Pharmaceuticals Inc REGN 366.61%
14 Incyte Corp INCY 366.43%
15 Sanofi SA SAN 360.47%
16 Merck & Co Inc MRK 360.06%
17 ImmunityBio Inc IBRX 332.01%
18 Ideaya Biosciences Inc IDYA 311.17%
19 Caris Life Sciences Inc CAI 271.26%
20 Arcus Biosciences Inc RCUS 243.88%
21 Ono Pharmaceutical Co Ltd 4528 189.00%
22 CRISPR Therapeutics AG CRSP 185.69%
23 Iovance Biotherapeutics Inc IOVA 181.91%
24 Novavax Inc NVAX 170.95%
25 USD CASH USD 165.17%
26 Nuvation Bio Inc NUVB 164.79%
27 ABCELLERA BIOLOGICS INC ABCL 155.54%
28 Vir Biotechnology Inc VIR 146.44%
29 Kura Oncology Inc KURA 102.32%
30 Janux Therapeutics Inc JANX 97.58%
31 CORVUS PHARMACEUTICALS INC CRVS 90.25%
32 SUNSHINE LAKE PHARMA CO LTD 6887 85.08%
33 GENFLEET THERAPEUTICS (SHANGHAI) I 2595 84.91%
34 Intellia Therapeutics Inc NTLA 79.58%
35 Personalis Inc PSNL 78.34%
36 RIGEL PHARMACEUTICALS INC RIGL 70.60%
37 CytomX Therapeutics Inc CTMX 61.26%
38 SHANGHAI HENLIUS BIOTECH INC H 2696 60.51%
39 DESIGN THERAPEUTICS INC DSGN 56.18%
40 Alvotech SA ALVO 52.98%
41 Ginkgo Bioworks Holdings Inc DNA 51.26%
42 Valneva SE VLA 50.93%
43 OCUGEN INC OCGN 49.50%
44 PACIFIC BIOSCIENCES OF CALIFORNIA PACB 48.02%
45 EUR CASH EUR 44.07%
46 VERASTEM INC VSTM 40.45%
47 ABCLON INC 174900 37.23%
48 Xencor Inc XNCR 33.86%
49 GBP CASH GBP 14.93%
50 JPY CASH JPY 12.79%

Sectors

Allocation by industry sector.
 
Sector Weight
Health Care 9277.00%
Unknown 723.00%

Regions

Geographic allocation by country of risk.
 
Country Weight
United States 5885.00%
Germany 791.00%
France 787.00%
UNKNOWN 723.00%
Japan 569.00%
Denmark 389.00%
United Kingdom 375.00%
Switzerland 367.00%
China 61.00%
Iceland 53.00%
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