iShares Biotechnology ETF
About
iShares Biotechnology ETF (US4642875565) is a US-listed equity ETF tracking the NYSE Biotechnology Index. With a expense ratio of 0.44%, its costs are on the higher end for an ETF, paying distributions. The fund holds 254 positions across 5 regions with 8.1B in assets, with heavy concentration — 89% in United States, 95% in Health Care.
Score Breakdown
Scores are scaled 1–10 on a logarithmic curve relative to all ETFs in the database. Last updated: Jun 22, 2026
| Component | Score | Details |
|---|---|---|
| Cost (30%) | 7.7 | Tracking Difference: 10.0 · TD Consistency: — · Expense Ratio: 2.5 |
| Liquidity (25%) | 10.0 | Assets Under Management |
Data sources: provider factsheets, exchange data, and NAV history. Information for educational purposes only — not investment advice.
Ticker IBB
ISIN
Fund Size $8.1B
Issuer iShares
Distribution Pays Distributions
Replication Physical
Inception Feb 2001
Base Currency USD
Index NYSE Biotechnology Index
Asset Class Equities
Category Thematic Equity
Costs
7.7 This fund has low total costs, with competitive tracking and expense ratios.
Expense Ratio0.00%
Expense Ratio0.00%
| Metric | Value |
|---|---|
| Expense Ratio | 0.44% |
Cumulative Returns
Performance across different time periods.
Year to Date+0.00%
1 Year+0.00%
3 Years+0.00%
5 Years+0.00%
Inception+0.00%
Year to Date+0.00%
1 Year+0.00%
3 Years+0.00%
5 Years+0.00%
Inception+0.00%
| Period | Cumulative Return |
|---|---|
| 1 Month | — |
| 3 Months | — |
| 6 Months | — |
| 1 Year | +41.86% |
| 3 Years | +11.21% |
| 5 Years | +2.85% |
| 10 Years | +6.60% |
| YTD | +2.17% |
| Since Inception | +6.90% |
Holdings
This fund invests into 254 individual investments.
View all holdings (50)
| # | Holding | Ticker | Weight |
|---|---|---|---|
| 1 | Vertex Pharmaceuticals Inc | VRTX | 800.54% |
| 2 | Amgen Inc | AMGN | 795.26% |
| 3 | Gilead Sciences Inc | GILD | 730.32% |
| 4 | Regeneron Pharmaceuticals Inc | REGN | 522.79% |
| 5 | ARGENX SE - ADR | ARGX | 387.47% |
| 6 | Alnylam Pharmaceuticals Inc | ALNY | 314.08% |
| 7 | Natera Inc | NTRA | 268.45% |
| 8 | REVOLUTION Medicines Inc | RVMD | 263.64% |
| 9 | Biogen Inc | BIIB | 244.40% |
| 10 | Illumina Inc | ILMN | 207.57% |
| 11 | Moderna Inc | MRNA | 197.40% |
| 12 | United Therapeutics Corp | UTHR | 187.03% |
| 13 | BEONE MEDICINES AG | ONC | 182.74% |
| 14 | Insmed Inc | INSM | 174.71% |
| 15 | Incyte Corp | INCY | 165.14% |
| 16 | Roivant Sciences Ltd | ROIV | 138.59% |
| 17 | Neurocrine Biosciences Inc | NBIX | 132.83% |
| 18 | ASCENDIS PHARMA | ASND | 121.30% |
| 19 | GENMAB SPONSORED ADR | GMAB | 112.13% |
| 20 | Exelixis Inc | EXEL | 107.39% |
| 21 | Ionis Pharmaceuticals Inc | IONS | 102.04% |
| 22 | Bridgebio Pharma Inc | BBIO | 95.17% |
| 23 | Madrigal Pharmaceuticals Inc | MDGL | 93.21% |
| 24 | Arrowhead Pharmaceuticals Inc | ARWR | 91.97% |
| 25 | Axsome Therapeutics Inc | AXSM | 91.63% |
| 26 | Medpace Holdings Inc | MEDP | 89.94% |
| 27 | BioMarin Pharmaceutical Inc | BMRN | 88.41% |
| 28 | Cytokinetics Inc | CYTK | 79.74% |
| 29 | Bio-Techne Corp | TECH | 76.78% |
| 30 | Krystal Biotech Inc | KRYS | 76.06% |
| 31 | Charles River Laboratories International Inc | CRL | 74.79% |
| 32 | Biontech Se | BNTX | 70.52% |
| 33 | Halozyme Therapeutics Inc | HALO | 68.36% |
| 34 | Praxis Precision Medicines Inc | PRAX | 62.61% |
| 35 | Alkermes PLC | ALKS | 62.29% |
| 36 | Vaxcyte Inc | PCVX | 61.69% |
| 37 | Repligen Corp | RGEN | 59.84% |
| 38 | Protagonist Therapeutics Inc | PTGX | 58.49% |
| 39 | Spyre Therapeutics Inc | SYRE | 58.00% |
| 40 | Nuvalent Inc | NUVL | 54.76% |
| 41 | Kymera Therapeutics Inc | KYMR | 54.64% |
| 42 | Rhythm Pharmaceuticals Inc | RYTM | 54.57% |
| 43 | ABIVAX AMERICAN DEPOSITARY SHARES | ABVX | 54.56% |
| 44 | Bruker Corp | BRKR | 54.04% |
| 45 | PTC Therapeutics Inc | PTCT | 53.76% |
| 46 | Tempus AI Inc | TEM | 45.63% |
| 47 | Mirum Pharmaceuticals Inc | MIRM | 45.12% |
| 48 | Twist Bioscience Corp | TWST | 44.32% |
| 49 | Apogee Therapeutics Inc | APGE | 43.73% |
| 50 | Cogent Biosciences Inc | COGT | 43.17% |
Sectors
Allocation by industry sector.
| Sector | Weight |
|---|---|
| Health Care | 9499.00% |
| Unknown | 501.00% |
Regions
Geographic allocation by country of risk.
| Country | Weight |
|---|---|
| United States | 8916.00% |
| UNKNOWN | 501.00% |
| Netherlands | 387.00% |
| Denmark | 121.00% |
| Germany | 71.00% |
| Iceland | 4.00% |
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