iShares Healthcare Innovation UCITS ETF

iShares Healthcare Innovation UCITS ETF

About

iShares Healthcare Innovation UCITS ETF (IE00BYZK4776) is a UCITS-compliant equity ETF tracking the STOXX GLOBAL BREAKTHROUGH HEALTHCARE. With a TER of 0.4%, it is moderately priced, reinvesting dividends. The fund holds 209 positions across 17 regions with 875M in assets, with heavy concentration — 68% in United States, 95% in Health Care.

ISIN
Fund Size $875.0M
Issuer iShares
Distribution Re-Invests Dividends
Replication Physical
Inception Sep 2016
Base Currency USD
Index STOXX GLOBAL BREAKTHROUGH HEALTHCARE
Asset Class Equities
Category Equity Sector

Costs

7.2
This fund has moderate costs compared to similar ETFs.

Cost Metrics Explained

What TER, tracking difference, and TD consistency measure

TER (Total Expense Ratio) is the annual fee the fund charges, deducted from assets. It’s the headline cost, but not the full picture.

Tracking Difference measures how much the fund actually lags (or leads) its benchmark index per year. This is the single best measure of true cost — it captures TER plus all other drags like sampling error and tax withholding. A lower (or negative) value is better.

TD Consistency measures how stable the tracking difference is from year to year. A low value means predictable, reliable costs; a high value means costs can vary significantly.
TER0.00%
Tracking Difference0.00%
TD Consistency0.00%

Cumulative Returns

Performance across different time periods.
1 Month+0.00%
3 Months+0.00%
Year to Date+0.00%
1 Year+0.00%
3 Years+0.00%
5 Years+0.00%
Inception+0.00%

Holdings

4.9
With only 209 individual holdings, this fund is relatively concentrated compared to other ETFs.
#1
E-MINI HEALTH CARE SECTOR SEP 26
13.00%
#2
RUSSELL 2000 EMINI CME SEP 26
6.00%
#3
USD CASH
2.54%
#4
UCB SA
2.32%
#5
Moderna Inc
1.95%
#6
GSK PLC
1.91%
#7
Novartis AG
1.89%
#8
Roche Holding AG
1.77%
#9
Genmab A/S
1.67%
#10
Roivant Sciences Ltd
1.57%

Sectors

1.1
This fund is concentrated in just a few of its 5 sectors, reducing diversification.

Regions

7.4
This fund invests across 18 countries, though its geographic allocation deviates somewhat from the global market.

Nerd Stuff

Advanced risk and return metrics (2023-06-20 — 2026-06-18).
10.9%
Volatility
-21.5%
Max Drawdown
0.07
Sharpe Ratio
0.10
Sortino Ratio
0.03
Calmar Ratio
0.29
Beta
-2.91%
Alpha (Jensen's)
0.082
R²
Benchmark-relative metrics (Beta, Alpha, R²) are calculated against the iShares Core S&P 500 ETF (IE00B5BMR087).

Documents

Regulatory and fund documents.
Key Information DocumentFact Sheet

Broker Availability

Where you can buy this ETF.
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